Effects of K76, an inhibitor of complement C5, on 5HT response to rO9 LPS.

The rO9 LPS (0.5 mg/kg) (a) was injected intravenously 1 hour after an intraperitoneal injection of saline. The rO9 LPS (1 m/kg) (b) was injected intravenously 1 hour after an intraperitoneal injection of K76 (100 mg/kg). Each value is the mean ± SD from 4 mice. *P < .05, **P < .01 versus corresponding value in the absence of K76.