Fig. 6.
Fig. 6. Anti–Crry F(ab)2 fragments enhance antibody-dependent rat cell–mediated cytotoxicity of allogeneic target cells. / 13762 rat mammary tumor cells were preincubated with PBS or increasing concentrations of anti–Crry F(ab)2. The target cells were then incubated in the absence or presence of anti–13762 polyclonal antibody as indicated, washed, and exposed to B-cell–depleted rat splenocytes (E/T ratio of 100:1). Lysis was determined by51Cr release assay after a 4-hour incubation. Figure shows means ± SD and is representative of 5 separate experiments.

Anti–Crry F(ab)2 fragments enhance antibody-dependent rat cell–mediated cytotoxicity of allogeneic target cells.

13762 rat mammary tumor cells were preincubated with PBS or increasing concentrations of anti–Crry F(ab)2. The target cells were then incubated in the absence or presence of anti–13762 polyclonal antibody as indicated, washed, and exposed to B-cell–depleted rat splenocytes (E/T ratio of 100:1). Lysis was determined by51Cr release assay after a 4-hour incubation. Figure shows means ± SD and is representative of 5 separate experiments.

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