American Society of Hematology

Fig. 4.

$Fig. 4. Reduced positive selection in mice with low p38 MAPK activity. / (Panel A) Expression of CD69 in total thymocytes from NLC mice and lck-MKK3(A)/MKK6(A) transgenic mice. The percentage represents the fraction of CD69+ thymocytes from NLC and line-2 transgenic mice. The average number of CD69+thymocytes from 6 NLC mice and 6 transgenic mice with extensive p38 suppression is indicated. (Panel B) TCR, CD5, CD69, and CD28 expression on CD4+CD8− and CD4−CD8+ thymocytes from NLC mice (open curve) and line-2 transgenic mice (filled curve).$

Reduced positive selection in mice with low p38 MAPK activity.

(Panel A) Expression of CD69 in total thymocytes from NLC mice and lck-MKK3(A)/MKK6(A) transgenic mice. The percentage represents the fraction of CD69⁺ thymocytes from NLC and line-2 transgenic mice. The average number of CD69⁺thymocytes from 6 NLC mice and 6 transgenic mice with extensive p38 suppression is indicated. (Panel B) TCR, CD5, CD69, and CD28 expression on CD4⁺CD8⁻ and CD4⁻CD8⁺ thymocytes from NLC mice (open curve) and line-2 transgenic mice (filled curve).

This Feature Is Available To Subscribers Only