KLH-specific proliferative responses induced by blood CD11c⁺ DCs, Mo-DCs, and ActMo-DCs.

(A,B) KLH-specific T-lymphocyte responses induced by 5 × 10³ blood CD11c⁺ DCs, Mo-DCs, and ActMo-DCs (generated in RPMI/5%AS, GM-CSF 200 U/mL, IL-4 50 U/mL and activated with LPS) loaded with 0 μg/mL to 100 μg/mL KLH for 3 hours (DC/T ratio; 1:20). Shown are 2 representative experiments with mean ± SD. (C,D) Paired KLH-specific T-lymphocyte responses induced by blood CD11c⁺ DCs, Mo-DCs, and ActMo-DCs loaded with 100 μg/mL KLH or (E,F) with 25 μg/mL KLH are shown as SI from 4 experiments.