Syk is not required for the fMLP-induced respiratory burst in suspension.

Wild-type or syk^−/− neutrophils were preincubated in the absence (A) or presence (B) of 10 μM CB and stimulated with the indicated concentrations of fMLP. For kinetic analysis of superoxide release, cells were stimulated with 3 μM fMLP. The fMLP dose-response curve was obtained from values after 5 minutes of stimulation.