Expression of HO-2 in the aortas of adult (20-week-old) and young (8-week-old) SHRs and age-matched WKYs.

Representative Western immunoblotting (A) and the mean relative abundant levels of expressed proteins (B) revealed a significantly lower HO-2 expression level in 8-week-old SHRs, which were unaffected by hemin treatment. *P < .05 versus age-matched WKYs. The ages of the animals in weeks are indicated by the numbers “20” and “8” in (A). n = 4 for each group. Error bars indicate means ± SEM.