Fig. 2.
Fig. 2. Elevation of IL-10, IFN-γ, sCD25, and sCD95-ligand in types 1-, 2-, 3-, and 4-deficient HLH. / Plasma concentrations of IL-10, IFN-γ, and the soluble receptors sCD25, sCD95-L were determined in patients with active HLH. Numbers of patients with type 1, type 2, type 3, and type 4 cytotoxic deficiency are given below the x-axis. Median values are indicated by a single bar within the column scatter. Values below or within the dashed horizontal line indicate the individual range of values determined in plasma of healthy controls (normal values, 0-10 pg/mL for IL-10 [n = 92]; 0-10 pg/mL IFN-γ [n = 60]; 200-1000 U/mL for sCD25 [n = 120]; < 50 pg/mL for sCD95-ligand [n = 39]).

Elevation of IL-10, IFN-γ, sCD25, and sCD95-ligand in types 1-, 2-, 3-, and 4-deficient HLH.

Plasma concentrations of IL-10, IFN-γ, and the soluble receptors sCD25, sCD95-L were determined in patients with active HLH. Numbers of patients with type 1, type 2, type 3, and type 4 cytotoxic deficiency are given below the x-axis. Median values are indicated by a single bar within the column scatter. Values below or within the dashed horizontal line indicate the individual range of values determined in plasma of healthy controls (normal values, 0-10 pg/mL for IL-10 [n = 92]; 0-10 pg/mL IFN-γ [n = 60]; 200-1000 U/mL for sCD25 [n = 120]; < 50 pg/mL for sCD95-ligand [n = 39]).

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