Fig. 10.
Fig. 10. Schematic diagram of the TCR-signaling pathway suppressed by RosA treatment. / The shaded area indicates the route of the TCR-signaling pathway that is affected by RosA treatment. Thin lines indicate protein-protein interactions and arrows indicate the directions of signaling. *Denotes the activated status and Ydenotes tyrosine phosphorylation. The figure schematically depicts 2 pathways, which are RosA susceptible, namely, the Ca2+-dependent pathway and the RosA-resistant, Ca2+-independent pathway.

Schematic diagram of the TCR-signaling pathway suppressed by RosA treatment.

The shaded area indicates the route of the TCR-signaling pathway that is affected by RosA treatment. Thin lines indicate protein-protein interactions and arrows indicate the directions of signaling. *Denotes the activated status and Ydenotes tyrosine phosphorylation. The figure schematically depicts 2 pathways, which are RosA susceptible, namely, the Ca2+-dependent pathway and the RosA-resistant, Ca2+-independent pathway.

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