Fig. 3.
Fig. 3. Effect of depletion of Ly49G2+ or Ly49C/I+ NK subsets in H2bxd F1mice on the engraftment of H2b allografts. / Mice were given various mAb treatments or NRS 2 days before irradiation. Irradiated mice (4 mice/group) received either 0.5 × 106 (A) or 20 × 106 parental-strain H2b BMCs (B). On the eighth day a soft agar colony assay was done to assess hematopoietic progenitor content in the spleens (mean ± SD). *Values significantly (P < .006) greater than mice receiving NRS in experiment A; **values significantly (P < .0004) greater than mice receiving NRS in experiment A; ***values significantly (P < .006) lower than mice receiving NRS in experiment B.

Effect of depletion of Ly49G2+ or Ly49C/I+ NK subsets in H2bxd F1mice on the engraftment of H2b allografts.

Mice were given various mAb treatments or NRS 2 days before irradiation. Irradiated mice (4 mice/group) received either 0.5 × 106 (A) or 20 × 106 parental-strain H2b BMCs (B). On the eighth day a soft agar colony assay was done to assess hematopoietic progenitor content in the spleens (mean ± SD). *Values significantly (P < .006) greater than mice receiving NRS in experiment A; **values significantly (P < .0004) greater than mice receiving NRS in experiment A; ***values significantly (P < .006) lower than mice receiving NRS in experiment B.

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