Fig. 1.
![Fig. 1. Effects of kallistatin on VEGF- and bFGF-induced proliferation, migration, and adhesion of HMVECs. / (A,B) Quiescent HMVECs were incubated with the indicated concentrations of human kallistatin (HKBP) and VEGF or bFGF (15 ng/mL) for 24 hours. DNA synthesis was measured as [3H]-thymidine incorporation. Each value represents mean ± SEM (n = 4). (C) Cell migration was determined using modified Boyden chambers. VEGF or bFGF, 15ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 3). (D) Cell adhesion was determined using fibronectin-coated plates. VEGF or bFGF, 15 ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 4).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/100/9/10.1182_blood-2002-01-0185/4/h82123311001.jpeg?Expires=1724237051&Signature=ovsUzNYA0rjoJsyPvsfU5brXroL2b85gk5fjTZE~lZc-mu9RwqRrAGBCLawHTd3zbcyvxN9VFqtotRkoO6luYNLc4nV8jWMXPYmw53FBUuqGiLCofuQOZN9XW7tf5-bGI7vKSL5dFwovUzcHrItzQcFlG2p3UHJS3QZeJfg3fDcR9HD~e2URICAH8j-GWR4jFXKhG9oxNc-m9OcrhgjsedX05XObkdqe7CeHe0xKIbyLgWIvXVTH9Og8k2Zbwdc4T2BTwWiT-UbXj5-ZmbaH4lGpdqTfsT3ES6rjmtJA5r3JSetjLNn7rolAoNds~GjOaK9PJ0VNXu8O7jrYYjAAUA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effects of kallistatin on VEGF- and bFGF-induced proliferation, migration, and adhesion of HMVECs.
(A,B) Quiescent HMVECs were incubated with the indicated concentrations of human kallistatin (HKBP) and VEGF or bFGF (15 ng/mL) for 24 hours. DNA synthesis was measured as [3H]-thymidine incorporation. Each value represents mean ± SEM (n = 4). (C) Cell migration was determined using modified Boyden chambers. VEGF or bFGF, 15ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 3). (D) Cell adhesion was determined using fibronectin-coated plates. VEGF or bFGF, 15 ng/mL; HKBP, 1μM. Each value represents mean ± SEM (n = 4).
