Blimp-1 is expressed in CD22+ and CD22⁻ B cells, and its expression is inversely correlated to Pax5 expression in the same cells.

P indicates MM patient. Superscripts “+” and “−” designate CD22⁺ and CD22⁻ B cells, respectively. (Lane M) A 100 bp ladder (Boehringer Mannheim). (Lane 1) A no-template control. (A) Full-length Pax5 expression in CD22⁺ and CD22⁻ B-cell populations from 4 patients. (B) Accompanying Blimp-1 expression in the same cell samples as panel A. (C) A β-actin control.