Sensitivity of SOCS3 transformants of KT-1/A3 to the antiproliferative effect of IFN-α.

Cells were incubated with 1000 U IFN-α for 72 hours and proliferation was assessed by MTT assay. Each point represents the mean ± SEM of 2 independent experiments, each conducted in triplicate. Statistical analysis (paired t test): A3 versus A6, F6, and mock versus A6, F6, P < .01.