ALK-1QD inhibits HMEC-1, HMVEC-l, and HUVEC migration in a wound assay.

These endothelial cells were infected for 15 hours with AdALK-1QD or Adβ-gal (MOI = 50). At 15 hours after infection, the cell monolayer was scratched to create a wound. The cells were observed by phase contrast microscopy and photographed at time 0 (wounding) and when the wound was closed in Adβ-gal–infected cells (24 hours for HMEC-1's, 48 hours for HMVEC-l's, and 32 hours for HUVECs). Original magnifications, × 50.