Fig. 3.
Fig. 3. Comparable efficiency of pDCs and CD11c+ DCs to stimulate an influenza HA–specific CD4+ T-cell clone. / HA136, a DRα1*0101/DRβ*0401-restricted influenza HA(307-319)–specific CD4+ T-cell clone, was cocultured with DRα1*0101/DRβ*0401+ pDCs or CD11c+ DCs infected by influenza virus or pulsed with influenza HA(307-319) peptide. (A) After 24 hours, IFN-γ in the coculture supernatants was measured by ELISA. (B) After 3 days,3H-thymidine was added for 12 hours to measure proliferation.

Comparable efficiency of pDCs and CD11c+ DCs to stimulate an influenza HA–specific CD4+ T-cell clone.

HA136, a DRα1*0101/DRβ*0401-restricted influenza HA(307-319)–specific CD4+ T-cell clone, was cocultured with DRα1*0101/DRβ*0401+ pDCs or CD11c+ DCs infected by influenza virus or pulsed with influenza HA(307-319) peptide. (A) After 24 hours, IFN-γ in the coculture supernatants was measured by ELISA. (B) After 3 days,3H-thymidine was added for 12 hours to measure proliferation.

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