Accelerated influx of cytolytic granzyme B⁺cells in the lungs of recipients of MIP-1α^−/− spleen cells.

Frequencies of cells expressing granzyme B mRNA were determined by in situ hybridization of cryosections with digoxigenin-labeled antisense RNA probes. (A) Mean values ± SE for 4 mice per group, pooled from 2 experiments. *P < .02 vs MIP-1α^+/+recipients. (B) In situ hybridizations for granzyme B for one mouse lung representative of each group shown in panel A for days 3 and 7 after BMT (× 200 magnification).