Fig. 1.
Fig. 1. Acceleration of GVHD-mediated mortality in the absence of donor MIP-1α. / Cy/TBI-conditioned B10.BR mice received transplants of C57BL/6 BM (■) plus either MIP-1α+/+ (○) or MIP-1α−/−(●) splenocytes. Recipients of MIP-1α−/− splenocytes had accelerated mortality compared with recipients of MIP-1α+/+ cells. (A) Survival. (B) Weights. Results shown are representative of 2 experiments (n = 10 per group;P < .0007).

Acceleration of GVHD-mediated mortality in the absence of donor MIP-1α.

Cy/TBI-conditioned B10.BR mice received transplants of C57BL/6 BM (■) plus either MIP-1α+/+ (○) or MIP-1α−/−(●) splenocytes. Recipients of MIP-1α−/− splenocytes had accelerated mortality compared with recipients of MIP-1α+/+ cells. (A) Survival. (B) Weights. Results shown are representative of 2 experiments (n = 10 per group;P < .0007).

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