Activation of the HTLV-1 and the Fuc-T VII promoters by CREB-1 or CREMα.

F9 teratocarcinoma cells were transfected with 4 μg reporter constructs, somatostatin-Luc (■), pU3R-Luc (░), or Fuc-T VII promoter (p(−791) (▪), and 0 to 4 μg pCGTax, together with 0 to 4 μg RSV-CREB (A) or 0 to 4 μg RSV-CREMα (B) and 4 μg RSV-PKA, as indicated. Resultant activities are plotted as fold induction normalized for CAT activity over that in the absence of Tax. Error bars depict the standard deviations from 3 independent experiments.