Fig. 5.
The responses of allogeneic naive CD4+ T cells to DCs derived from CML patients are heterogeneous.
DCs were generated from healthy individuals (○) and from CML patients (●): patient 5 (A), patient 3 (B), and patient 4 (C). Different numbers of immature (dotted lines) or mature (solid lines) DCs were cultured with naive CD4+ T cells purified from cord blood. After 5 days, 3HTdR was added and thymidine incorporation was measured after 20 hours. The data are expressed as counts per minute (cpm) ± standard deviations (SD). The results are representative of 10 experiments obtained with DCs derived from different patients as indicated in Table 1.
