Platelets change shape normally in the absence of WASp.

Platelets isolated from a healthy volunteer (A), WAS patient P39 (B), and wild-type (C) and WASp-deficient mice (D) were allowed to adhere on CRP-coated glass coverslips. Images shown are captured 10 minutes after the initial adhesion and activation reaction. Results shown are representative of the 3 patients studied. Filopodia are indicated by a white arrow.