Effect of rh MIP-1α and MIP-1β on OCL formation and function in vitro.

rhMIP-1α and MIP-1β were added at the indicated doses to rabbit bone cell cultures. The data represent the number of TRAP⁺MNCs (open bars) and pits on dentine slices (hatched bars). Results were expressed as a mean of 5 samples with an error bar of SD. * and ** indicate significantly different from the control culture in the number of TRAP⁺ MNCs and pits, respectively (P < .05, ANOVA with Scheffe post hoc tests).