TRALI cases by blood component type after implementation of a male donor plasma mitigation strategy. TRALI cases classified in the American Red Cross hemovigilance program are expressed per million distributed components for transfusions involving only a single component type. The black stacked bars are reported fatalities. Lines show 95% confidence intervals (95% CIs) for the overall TRALI rates (fatal and nonfatal cases). OR, odds ratio; PLT, platelet. Reprinted from Eder et al¹⁰⁴  with permission.