The hemogram: cell numbers in health, disease, and after transfusion. (A) Normal. (B) Counts typical for hematological malignancy. (C) Transfusion impact/goal. Assumptions: 5-L blood volume and middistribution values, 5 trillion cells per RBC unit (u), and 300 billion PLTs per adult dose concentrate. Hb, hemoglobin; WBC, white blood cell.