Fig. 2.
Fig. 2. Parenteral ATO prolonged QTc and APD. / (A) Acute feeding of ATO resulted in progressive dose-dependent prolongation of QTc. *P < .05 versus control; #P < .01 versus control; +P < .001 versus control. (B) Chronic feeding of ATO produced time-dependent prolongation of QTc. *P < .05 versus control; #P < .01 versus control. (C) APD of papillary muscle after eighth day chronic feeding of ATO, showing longer APD90 in ATO-treated ones. #P < .01 versus control; +P < .001 versus control.

Parenteral ATO prolonged QTc and APD.

(A) Acute feeding of ATO resulted in progressive dose-dependent prolongation of QTc. *P < .05 versus control; #P < .01 versus control; +P < .001 versus control. (B) Chronic feeding of ATO produced time-dependent prolongation of QTc. *P < .05 versus control; #P < .01 versus control. (C) APD of papillary muscle after eighth day chronic feeding of ATO, showing longer APD90 in ATO-treated ones. #P < .01 versus control; +P < .001 versus control.

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