Fig. 2.
Fig. 2. SRC and PI-3 kinases are required for Fcγ receptor–mediated phagocytosis. / J774A.1 cells were treated with (A) PP1 or (B) wortmannin at the indicated concentrations along with an appropriate DMSO control for 1 hour in DMEM with 10% FCS and then IgG-sensitized sRBCs were added at a target-to-effector ratio equal to 100:1. Columns indicate phagocytic index of J774A.1 cells treated with DMSO (control), PP1, or wortmannin (mean ± SD).

SRC and PI-3 kinases are required for Fcγ receptor–mediated phagocytosis.

J774A.1 cells were treated with (A) PP1 or (B) wortmannin at the indicated concentrations along with an appropriate DMSO control for 1 hour in DMEM with 10% FCS and then IgG-sensitized sRBCs were added at a target-to-effector ratio equal to 100:1. Columns indicate phagocytic index of J774A.1 cells treated with DMSO (control), PP1, or wortmannin (mean ± SD).

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