Fig. 7.
![Fig. 7. Allogeneic, HLA-matched MLR. / HLA.A2+ CLL cells were infected with either AAV/CD40L or AAV/EGFP and incubated for 72 hours with naive CLL cells (1:10) derived from the same patient. Then 1 × 104 CLL cells irradiated with 200 Gy were cocultured with 1 × 105 purified healthy donor T cells (HLA.A2+) for another 96 hours, pulsed with [3H]-thymidine and T-cell proliferation determined 6 hours later (cpm). The data from one representative patient are depicted. Error bars represent SEM of triplicate measurements.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/100/5/10.1182_blood.v100.5.1655.h81702001655_1655_1661/3/h81723031007.jpeg?Expires=1725323788&Signature=smjpJ5eWATrdgAyL2761h6~CquTyiWrETFIrZXp~SzaXL6VzI0Q2Sm3qL2Gy7nvnAIZb9tL8tAwjpQO51HvdsgxG99LvOQK1SngVegCN~Ytg3VLUHstgR05kPZ9mm5OndtUvP-OyLPWZkj4YPJmKet6gwz0Dw4ki6rOSF3wF~rb58i1jpuHU6DxFELTMoHX9VYIA7GpVuX86YCrwikek4iDlNouOH37cUCJ4jrCAKMSM-Nz20pHIZ3dO0zO8vZbiUAceZC2QxJF0KyScWHNJa7C2gb5gDZ8aWXeGww00CYyi~F-nJmoIIOFCgYCaY80KgklYMpWoOdJKMHfHVppTJw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Allogeneic, HLA-matched MLR.
HLA.A2+ CLL cells were infected with either AAV/CD40L or AAV/EGFP and incubated for 72 hours with naive CLL cells (1:10) derived from the same patient. Then 1 × 104 CLL cells irradiated with 200 Gy were cocultured with 1 × 105 purified healthy donor T cells (HLA.A2+) for another 96 hours, pulsed with [3H]-thymidine and T-cell proliferation determined 6 hours later (cpm). The data from one representative patient are depicted. Error bars represent SEM of triplicate measurements.
