Distribution of allelic imbalances and complete LOH/biallelic losses.

Frequencies of allelic imbalances (yellow) and complete LOH and biallelic losses (blue) per informative patient. See legend in figure for color code. Microsatellite markers per chromosome according to the Généthon map and the NCBI GeneMap '99. Microsatellite markers D4S1597, D16S515, and DXS1226 resulted in PCR failures and are not shown. As allelic imbalances in regions with clonal deletions (complete LOH and biallelic losses) most likely represent subclonal deletions, their frequencies are included in the blue column.