Fig. 6.
Dose-response effect of compstatin and anti-C5a antibody on E coli–induced oxidative burst in granulocytes and monocytes.
One representative of 5 experiments is shown. The oxidative burst is given as median fluorescence intensity (MFI). ▵ indicates baseline value (T0); ▴, whole blood incubated 10 minutes with E coli (1 × 108 bacteria per milliliter), ●,E coli plus compstatin; ○, E coli plus control peptide, ▪, E coli plus anti-C5a; ■ isotype-matched control antibody.
