American Society of Hematology

Fig. 5.

$Fig. 5. Rescue of reduced factor-independent growth of single BCR-ABL-transduced IL-3−/−BM cells by restoration of IL-3 production. / (A) Percentage of transduced cells generating clones of more than or equal to 2 refractile cells after 7 days in the absence of added growth factors. Values shown are the means ± SEM from 3 experiments with each genotype of BM cells. (B) Clone size distributions obtained from single BCR-ABL ± IL-3–transduced IL-3−/− cells by comparison to BCR-ABL–transduced +/+ cells after being cultured for 7 days in the absence of growth factors. Data for a representative experiment of 3 performed are shown.$

Rescue of reduced factor-independent growth of single BCR-ABL-transduced IL-3^−/−BM cells by restoration of IL-3 production.

(A) Percentage of transduced cells generating clones of more than or equal to 2 refractile cells after 7 days in the absence of added growth factors. Values shown are the means ± SEM from 3 experiments with each genotype of BM cells. (B) Clone size distributions obtained from single BCR-ABL ± IL-3–transduced IL-3^−/− cells by comparison to BCR-ABL–transduced +/+ cells after being cultured for 7 days in the absence of growth factors. Data for a representative experiment of 3 performed are shown.

This Feature Is Available To Subscribers Only