Figure 1.
Cold agglutinin–associated lymphoproliferative bone marrow disease. Bone marrow trephine biopsy showing intraparenchymatous nodular lymphoid lesions (A-B, hematoxylin and eosin staining, original magnification ×40 and ×200, respectively). Immunoperoxidase staining for CD20 highlights intraparenchymatous nodular B-cell infiltration (C, original magnification ×200). Mast cells are not discerned around the nodular lymphoid lesions (D, Giemsa staining, original magnification ×200). Reprinted from Randen et al4 with permission.
