Modulation of CD3 antigen expression on T cells after incubation with CD3 antibodies.

(♦, BM^WT), bivalent^WT monomer; (▵, BD), bivalent^Cys444 dimer; (×, MD), monovalent^Cys444 dimer; (⋄, alem), CD52 mAb alemtuzumab. Each point is the mean of duplicate samples. The mean fluorescence values have been corrected using a no first antibody control.