Fig. 1. Erythrocyte capture by platelets and dependence on platelet activation state. / (A) One of many short-lived pausing events observed as washed erythrocytes were perfused over collagen-adherent platelets at a wall shear rate of 50 sāˆ’1. Following capture, membrane tethering, and a pause for 400 milliseconds, the red cell was released by the platelet. Visualization of firmly adhered erythrocytes on fibrinogen-adherent platelets (B) or collagen-adherent platelets (C) demonstrated the dependence of RBC adhesion on platelet activation. Identical results were obtained in 3 separate experiments, each conducted with an individual donor. Flow was from right to left.
Fig. 1.

Erythrocyte capture by platelets and dependence on platelet activation state.

(A) One of many short-lived pausing events observed as washed erythrocytes were perfused over collagen-adherent platelets at a wall shear rate of 50 sāˆ’1. Following capture, membrane tethering, and a pause for 400 milliseconds, the red cell was released by the platelet. Visualization of firmly adhered erythrocytes on fibrinogen-adherent platelets (B) or collagen-adherent platelets (C) demonstrated the dependence of RBC adhesion on platelet activation. Identical results were obtained in 3 separate experiments, each conducted with an individual donor. Flow was from right to left.

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