Identification of dermal TRANCE⁺RANK⁺ cells.

Immunolabeling of healthy human skin for TRANCE, RANK, and other antigens as indicated (B-E). (A) Arrows highlight double-positive cells. (B) Arrows point to dermal blood vessels. (E) Arrowheads highlight CD1a⁺ cells in the dermis. (F) Incubation with TRANCE isotype control and rabbit preimmune serum. In all panels, ep indicates epidermis; d, dermis. Original magnification: A, C, D × 160; B, E, F × 125. Development was done using Fast Blue and 3,3′ diaminobenzidine (DAB).