Fig. 1.
Fig. 1. IAP gene family expression in normal and neoplastic B cells. / Expression of XIAP, survivin, NAIP, c-IAP-1, c-IAP-2, and TRPM2 mRNA in B lymphocytes from patients with B-CLL (lanes 1-8), healthy blood donors (lanes 9-14), the human B-cell precursor lines MHH-CALL2 (lane 15), MHH-CALL3 (lane 16), MHH-CALL4 (lane 17,) and the human myeloma cell lines LP-1 (lane 18), OPM-2 (lane 19), NCI-H929 (lane 20), and RPMI-8226 (lane 21). A hAPO-5c RNAse protection assay with an added TNFα template provided by the manufacturer was used. A quantity of 10 μg total RNA was used per lane.

IAP gene family expression in normal and neoplastic B cells.

Expression of XIAP, survivin, NAIP, c-IAP-1, c-IAP-2, and TRPM2 mRNA in B lymphocytes from patients with B-CLL (lanes 1-8), healthy blood donors (lanes 9-14), the human B-cell precursor lines MHH-CALL2 (lane 15), MHH-CALL3 (lane 16), MHH-CALL4 (lane 17,) and the human myeloma cell lines LP-1 (lane 18), OPM-2 (lane 19), NCI-H929 (lane 20), and RPMI-8226 (lane 21). A hAPO-5c RNAse protection assay with an added TNFα template provided by the manufacturer was used. A quantity of 10 μg total RNA was used per lane.

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