American Society of Hematology

Fig. 1.

$Fig. 1. B-cell development in the thymus is blocked at the pro–B-cell stage. / (A) Phenotype of CD45R+CD43+ pro–B cells harvested directly from the bone marrow (BM) or thymus (THY) of BALB/c mice. The frequency of cells in fractions A, B, C, and C′ stages of development was assessed by analysis of Ly51 (BP-1) and CD24 expression on the gated CD45R+CD43+ cells. (B) Cell cycle status of pro–B cells in the BM and thymus. Data in the figures are representative of 3 experiments.$

B-cell development in the thymus is blocked at the pro–B-cell stage.

(A) Phenotype of CD45R⁺CD43⁺ pro–B cells harvested directly from the bone marrow (BM) or thymus (THY) of BALB/c mice. The frequency of cells in fractions A, B, C, and C′ stages of development was assessed by analysis of Ly51 (BP-1) and CD24 expression on the gated CD45R⁺CD43⁺ cells. (B) Cell cycle status of pro–B cells in the BM and thymus. Data in the figures are representative of 3 experiments.

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