Response to thalidomide is associated with reduced microvessel density.

Values are means ± SEM for all responding (n = 7) and nonresponding (n = 7) hosts. In responsive thalidomide-treated hosts, microvessel density was significantly lower than in CMC-treated controls (P < .02). There was no difference in microvessel density between control and thalidomide-treated hosts among the nonresponders.