Serial measurements of IGF-1 and IGFBP-3 from diagnosis to death or last follow-up in 4 MM patients.

Serum M-protein levels were derived from medical records. For details, see “Results.” Dotted line indicates treatment periods; asterisk, initiation of new treatment; IGFBP-3, ▪; s-M protein, ▴; IGF-1, ■; and +, death.