Figure 2.
Figure 2. BCLU with MYC and BCL6 double-hit. (A) There is a diffuse proliferation with a starry sky pattern due to tingible body macrophages like in a BL. (B) At high magnification, note the rather monotonous proliferation of intermediate-size transformed cells and scattered tingible body macrophages. Although resembling a BL, there are more cells with single central nucleoli than would be typical and some irregular nuclear contours. The Ki-67 stain was extremely high but, unlike BL, the cells were CD10 negative and BCL2 positive (not illustrated).

BCLU with MYC and BCL6 double-hit. (A) There is a diffuse proliferation with a starry sky pattern due to tingible body macrophages like in a BL. (B) At high magnification, note the rather monotonous proliferation of intermediate-size transformed cells and scattered tingible body macrophages. Although resembling a BL, there are more cells with single central nucleoli than would be typical and some irregular nuclear contours. The Ki-67 stain was extremely high but, unlike BL, the cells were CD10 negative and BCL2 positive (not illustrated).

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