Figure 2.
Figure 2. Suggested algorithm for reversing VKAs in nonbleeding patients with an INR above the therapeutic range. For patients with a single INR of ≤0.5 above the therapeutic range, the VKA dose should remain unchanged. *With acenocoumarol, consider merely reducing the dose because stopping may result in INR overcorrection. **With acenocoumarol, stopping for more than 1 day may result in INR overcorrection. §Patients with older age, heart failure, cancer, or longer acting VKA.

Suggested algorithm for reversing VKAs in nonbleeding patients with an INR above the therapeutic range. For patients with a single INR of ≤0.5 above the therapeutic range, the VKA dose should remain unchanged. *With acenocoumarol, consider merely reducing the dose because stopping may result in INR overcorrection. **With acenocoumarol, stopping for more than 1 day may result in INR overcorrection. §Patients with older age, heart failure, cancer, or longer acting VKA.

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