Cumulative incidence (CI) of relapses in MRD-based risk groups in precursor-B-ALL treated in AIEOP-BFM ALL 2000¹⁹  MRD-standard risk (SR) means no MRD detectable at days 33 and 78 from diagnosis (sensitivity for 2 targets must be at least 10-⁴); MRD-HR means that the MRD level at day 78 is ≥ 10-³; and MRD-intermediate risk (IR) is all other constellations of MRD.