Premature ovarian failure after radiation therapy. Graphs demonstrating the age at which a patient may be predicted to experience ovarian failure (with 95% confidence intervals) at total body irradiation doses of 3, 6, 9, and 12 Gy. Patients over the age of 11 years are shown in green, whereas under age 11 is in red; age 11 is the earliest age that ovarian failure may be detected biochemically.¹⁸