Table 1.

Recommendations from the European LeukemiaNet for the Management of CML

Recommendations from the European LeukemiaNet for the Management of CML4

MMR indicates BCR/ABL1 <0.1%; CCA/Ph+, clonal chromosomal abnormalities in Ph+ cells; and CCA/Ph−, clonal chromosomal abnormalities in Ph− cells.

* Loss of MMR should be confirmed in 2 consecutive quantitative RT-PCR tests, of which one has a BCR/ABL1 transcripts level >1%.

Monitoring is performed by metaphase cytogenetics on bone marrow aspirate sample and/or by quantitative RT-PCR for BCR/ABL1 transcript levels on blood samples.

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