Meta-analysis of Papaemmanuil et al²³  2016 data for broad patterns of genomic instability in AML shows that ∼20% of patients with AML were defined according to fusion genes, 31% by chromosomal aneuploidies (to include at least 1 aneuploidy), 46% by gene mutations only (in the absence of gene fusions and chromosomal aneuploidies), and 3% with no events.