Table 1.
Standard frontline therapy for advanced stage, nonlymphoblastic, pediatric NHL
C indicates cyclophosphamide; V, vincristine; P, prednisone; M, methotrexate; D, doxorubicin; AraC, cytarabine; E, etoposide; Dex, dexamethasone; I, ifosfamide, Vb, vinblastine; 6MP, mercaptopurine; 0.5, 0.5 g/m2; 3, 3 g/m2; 8, 8 g/m2; CNS, central nervous system.
* Modified EPOCH (E, D, V, C, and P) with rituximab is now favored for the treatment of primary mediastinal B lymphoma in adult patients and being explored in pediatric patients. Lymphoblastic lymphomas are for the most part treated on acute lymphoblastic leukemia trials in pediatric patients.
