(A) How we approach the management of ET and PV. (B) How we approach nontransplant management of MF. CV, cardiovascular; Epo, erythropoietin; ESA, erythropoiesis-stimulating agent; Hct, hematocrit; HU, hydroxyurea; PBT, phlebotomy; Plts, platelets; symptoms (bone pain, fever, night sweats, and weight loss).