Prevalence of SCIs in unselected children and adults with SCA, and the prevalence of SCIs in children and young adults with SCA. The figure displays the cumulative prevalence of SCIs in children and young adults based on 6 studies.^27-32  The cumulative prevalence of SCIs suggests that the incidence of SCI does not plateau, but rather steadily increases through 30 years of age.²⁷  Figure reproduced from Kassim et al.²⁷