Figure 2.
Figure 2. Distribution and frequency of reported germ line mutations in ETV6. The ETV6 protein is diagrammed with its pointed (SAM_PNT) and canonical ETS family DNA binding (Ets) domains. Germ line mutations associated with leukemia are clustered in the Ets domain, but spread throughout the protein.

Distribution and frequency of reported germ line mutations in ETV6. The ETV6 protein is diagrammed with its pointed (SAM_PNT) and canonical ETS family DNA binding (Ets) domains. Germ line mutations associated with leukemia are clustered in the Ets domain, but spread throughout the protein.

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