Scattergram of pituitary volume versus pituitary iron. Because normal values are age dependent, results are displayed as Z-scores according to published nomograms.³⁷  Normal pituitary iron and size (Z ≤ 2) is represented by the clear box. Solid dots represent patients with normal gonadal function, clinically, and X's represent patients with clinical hypogonadism. (Figure redrawn with permission from Noetzli et al.⁴¹ )