Table 5.

Summary of risk factors for outcomes following allogeneic HCT for AML in older adults

Summary of risk factors for outcomes following allogeneic HCT for AML in older adults

“Important factors with strong evidence” means that these factors have strong discriminative capacity for outcomes based on a significant amount of evidence in the literature; these factors should be used routinely for risk assessment before allogeneic HCT in older AML patients. “Less or nonimportant factors” means that results from available literature suggest weak or lack of discriminative capacity of these factors for HCT outcomes in older patients; these factors should not be used solely for decision making about allogeneic HCT. “Apparently important but requires stronger evidence” means that evidence from the literature in allogeneic or non-allogeneic HCT settings suggests prognostic significance of these factors, but the available information is insufficient and additional details in prospective and retrospective studies are warranted; inclusion of these factors, if available, in risk assessment before allogeneic HCT is preferred. “Factors of interest, requires additional information means that evidence is weak about the prognostic significance of these variables for HCT outcomes; future investigations into the significance of these variables are required; inclusion of these factors in risk assessment before allogeneic HCT in older adults is currently discouraged.

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