Canonical discriminant analysis of VOCs to distinguish GVHD and response. (A) Canonical discriminant analysis used 5 VOCs to classify patients as GI GVHD or no GI GVHD. Discriminant function scores based on linear combinations of these 5 VOCs are shown for 29 patients. Three patients were misclassified (M) by using this discriminant model. (B) Receiver-operating characteristic curve for the discriminant analysis model that used the 5 VOCs to classify patients as GI GVHD or no GVHD. (C) CDA used 2 VOCs to classify day 28 response in patients with GI GVHD. Discriminant function scores based on linear combinations of these 2 VOCs are shown for 19 patients. Three patients were misclassified (M) by using this discriminant model. AUC, area under the curve; CI, confidence interval.