Effect of antibiotic therapy on visual tumors in a patient with CTCL. (A) The patient was diagnosed with MF in 2003 presenting patch/plaque lesions localized in the axillary skin area. (B-C) Despite intensive systemic and topical antitumor therapy, the disease progressed. (C) The patient developed severe sepsis and was treated with IV antibiotics (carbapenem). At this timepoint, the patient was in a critical condition and was not treated with CTCL-directed anticancer therapy. (D) An almost complete clearance of the tumor burden was observed after IV antibiotic therapy.